Located in the middle Jiangnan orogenic belt, the Dahutang ore concentration area in northern Jiangxi Province is famous for producing world-class superlarge tungsten ore deposits and large copper ore deposits, thus serving as one of the largest discovered tungsten producing base area in recent years. This study is aimed at investigating the W, Cu and Mo mineralization features and ore-forming age in different rock units of Yanshanian period in the Shimensi ore district. Scheelite mainly occurs in porphyritic granite and the external contact zone of the wall rock with veinlet-disseminated granite. Chalcopyrite and molybdenite are mainly existent in porphyritic granite, fine-grained granite, granite porphyry and the contact zone of wall rock with disseminated granite. Ore chemical composition indicates that the components of sulfides are relatively uniform in three sets of rock units with the following data:chalcopyrite (Cu 34.215%~35.161%, Fe 29.206%~30.721%, S 34.388%~35.520%) and molybdenite (Mo 59.44%~60.54%, S 40.067%~40.370%). The molybdenite Re-Os isotopic model average ages are 143.3 Ma, 145.2 Ma, 144.5 Ma, 143.6 Ma respectively in porphyritic biotite granite, fine-grained biotite granite, biotite granite porphyry and thick-vein quartz, which are basically identical within the error range, indicating that Cu, Mo mineralization were formed in one metallogenic epoch. Therefore the molybdenite Re-Os isotopic isochron age of 145.1±1.0 Ma (MSWD=0.46) could represent the mineralization time of Cu, Mo. Combined with the previous study of granites in Dahutang, the authors hold that the mineralization of scheelite and Cu, Mo took place in two metallogenic epochs in the Shimensi ore district. The former was closely related to the porphyritic granite and the latter probably had metallogenic relationship with the granite porphyry of late Yanshanian period. The ore-forming materials were delivered from granite porphyry to other rock units to cause mineralization gradually.