This paper introduces the general theory and method on analysis the co- mposition of fluid inclusions with MOLE raman microprobe. At present, the destructive analytic method is bing used in the ana lysis of the composition of fluid inclusions. But 'this method can't distinguish orignal and seconoary fluid inclusion and the solution of host minerals affects analytic results. The analysis of fluid inclusion with MOLE raman microprobe is non-destructive and point analytic method. The analytic results are satisfactory. Seven fluid inclusions have been analysed by the MOLE raman miceoprobe One of them is the fluid inclusion in quartz from Danzhai mercur y depcsit. The compsition of gaseous phase are CO2 42%,N2 37 % CH4 21%.The compsi- tion of liquid phase is mainly water the salinity 8 wt % . The douehter minerals in the fluid inclusions also have been determined to be calcit. The sample is fluorite of mineralization period in No 335 uranium deposit, Guang-Dong province. The fluid inclusions in fluorit from No 681 uranium ,deposit,Zhe-Jiang province contain CO2, H2S. The article also introduces Dhamelincourt's work on study of fluid inclu- sions with MOLE raman microprobe.