The Mesozoic granites, especially Late Jurassic, are widely distributed in Jiaobei terrane. To further understanding the formation age, genesis and geodynamic background of these granites has great significance to the crustal evolution of study area. In this paper, the major and trace elements, zircon U-Pb ages and O isotopes of the Jurassic granites in the eastern and northern Jiaobei terrane are reported. The results show that the zircon U-Pb ages of the granites studied in this paper are mainly distributed between 166 Ma and 156 Ma, representing the crystallization age of the granites. In addition, there are a large number of inherited zircons with age peaks of 3 650~3 294 Ma, 2 660~2 445 Ma, 770~600 Ma and 245~197 Ma. These granites shown adakite-like geochemical characteristics. The formation ages and geochemical characteristics of Jurassic granites in this study are similar to those of Linglong and Luanjiahe Jurassic granites from western Jiaobei terrane, indicating a similar source from partial melting of thickened continental lower crust. Furthermore, based on the variation of the U-Pb age and O isotope of inherited zircons from different samples, we concluded that the Jurassic granites in Jiaobei terrane have multiple sources, some of them derived from the thickened continental lower crust in Jiaobei terrane and the others from subducted Yangtze block. Then, the subduction of Paleo-Pacific or Izanagi plate might play a direct or indirect role in causing the partial melting of the thickened continental lower crust.