The Nariniya lead-zinc deposit, recently discovered in the Tibetan Plateau, is genetically linked to the activities of potassic volcanic magma. Studies show that the SiO₂ and K₂O content of the fresh host rocks is 62.9%～68.6% and 5.1%～5.8%, respectively, indicative of a shoshonitic series. The host rocks are relatively enriched in LREE and large iron lithophile elements and strongly depleted in elements such as Nb, Ta, and Ti. The Sr/Y ratios and Y content fall into the range of the potassium-ultrapotassic rocks, which has already been reported. These data suggest that the magma was sourced from enriched mantle or the asthenosphere mantle which had been contaminated by lower crustal material. Ore bodies occur as NWW-striking veins in volcanic rocks, consisting of galena, pyrite, quartz, calcite, dolomite, and minor sphalerite, chalcopyrite, and sericite. The alteration is dominated by muscovitization and pyritization. Fluid inclusions in quartz belong to a H₂O-NaCl system and have the homogenization temperature of 170～300℃ and the salinity of 2%～9% NaCl_eq, which probably represents meteoric water driven by magmatic activity. The δ³⁴S values of galena are from -0.1 to 1.7 and the Pb isotopic compositions fall into the range of the potassium-ultrapotassic rocks of northern Tibet, so the sulfur and lead were probably derived from the potassic volcanic rocks. The Nariniya lead-zinc deposit is significantly different from carbonate-hosted lead-zinc deposits in Tuotuohe region in geological and geochemical characteristics, so they belong to different ore-forming systems.