High voltage pulse fragmentation is an advanced sample comminution technology. Based on this technique, SefFrag A G Company in Switzerland manufactured a high voltage pulse fragmentation machine, called SelFrag High Voltage Pulse Fragmentor. This instrument can generate 90～200 kV high voltage, and then shortly discharge the energy from HV working electrode to solids under water. The solids will disaggregate along grain boundaries, inclusions or inhomogeneities, and the minerals such as zircon and apatite in the solid rocks will be completely liberated keeping the morphology intact. Compared with conventional mechanical methods, this highly selective fragmentation has many advantages: ① easy washing with no contamination, ② working in the water with no dust, ③ no loud noise, ④ selective fragmentation without destroying mineral crystals. Currently, the SelFrag High Voltage Pulse Fragmentor is applied in selecting minerals from rocks for geoscience. Besides, it is applicable to circuit waste recycle.