This paper has studied characteristic values and upward changing tendency ofεNd(t),t2DMand fANd in granitic rocks of 430 granite body as well as the variation of these values in linear- and planar-greisens of Xi-anghualing. Nd isotopic characteristics of rocks suggest that the granite resulted from the mixing of the crust material with the mantle material, and that the mantle material derived from the deep source got into and was distributed unevenly in the granite body. The mantle material might have mainly taken the form of mantle fluid to join the process of granitic evolution. Under the Mesozoic background of lithosphere thinning in East China,the mantle fluid underplating induced the remelting of Mesoproterozoic strata, forming granitic magma.