The kinetics of interface reaction of environmental minerals is subjected to study the reaction rate of the toxic metal ions or hazard organic molecular on the mineral surfaces in earth surface environments and explore their interface reaction mechanism. On the mineral surfaces there exists a sort of functional groups that have very strong chemical activity. During the migration of the toxic metal ions or organic molecule on earth surface they would be reacted with the mineral surfaces and have different driving force and reaction rate for both of the surface functional groups and ions or molecule have different polarity, charge and Lewis acidity. These reactions process will forth control existing forms and stability of the toxic matter, as well as their migration and transformation in atmosphere, water system and sediments. This article gives a brief introduction about the kinetic theory of the interface reaction of environmental minerals and some application examples.