The Manono region of the DRC is rich in pegmatite-type lithium, tin, niobium and tantalum resources. In the historical production process, only tin and niobium tantalum minerals were recovered, while lithium-containing minerals were discharged with tailings and stored until now. To determine the occurrence characteristics of lithium-containing minerals in tailings, the process mineralogy of lithium-containing minerals in tailings samples was studied by particle size analysis, X-ray fluorescence spectroscopy (XRF), chemical multi-element analysis, X-ray diffraction, scanning electron microscopy, and other comprehensively methods. The results indicate that the Li₂O grade of the lithium-containing tailings sample is 1.05%, and 95.04% of the lithium element in the ore is distributed in spodumene. The mineral content of spodumene in the raw tailing ore sample is 13.1%. Spodumene is mainly distributed in medium-coarse grains and has a simple association with other minerals, with low weathering degree. The Li₂O content in spodumene is 7.9%. Through the study of process mineralogy of lithium-containing minerals, it has been determined that the lithium-containing tailings belong to the spodumene-type (tailings) deposit, with good mineralogical indicators for mineral processing, providing a technical basis for the recovery of spodumene from tailings.