Abstract:In this study, the authors chose 123 breast pathological mineralization samples and made a micro-morphology classification study using optical microscope as well as scanning electron microscope. Then, the relationships between the type of breast mineralization and the age of the patient as well as the type of breast lesion and the stage of cancer were discussed by using statistical methods. Based on the resolvable morphology under the optical microscope, the authors divided the mammary mineralization into two types:granular aggregates and massive aggregates; granular aggregates are regular granular calcifications less than 200 μm, with a few having rings. The band structure is tightly bound to the organic structure; the block aggregate is assembled by flaky calcification with the size more than 200 μm, and the aggregates' shape is irregular. Statistical analysis shows that, with the increase of age, the pathological proportion of the aggregates increases, while the pathological proportion of the granular aggregates decreases, and the sensitive age partition is 50 years old; the granular aggregates appear separately in patients over 50 years old and under 50 years old. The probabilities are 24% and 53%, respectively; the mass aggregates are predominant in patients with breast carcinoma in situ (71.4%), and the granulating aggregates are predominant in patients with breast fibroadenomas (64.5%). This study can provide a new auxiliary method for the diagnosis of breast cancer based on the refined mineralogical feature of breast mineralization.