In this paper, the authors analyzed the characteristics of the CIA distribution curve of Liantuo Formation in Nanhua System in South China, and compared different CIA values as well as their explanations for the paleoclimate. Compared with the lithofacies-paleoclimate analysis method, the result does not show consistency in the paleoclimate characteristics. By means of analog method and in comparison with the cold paleoclimate of the overlying Nantuo Formation, it is found that the interglacial period sediment is very monotonous in Nantuo Formation, whereas it is abundant in Liantuo Formation and has various sedimentary structures. The factors controlling the accuracy of CIA values mainly include the lithology of samples, sampling precision and the source-to-sink system. It can be said that the source rock composition and weathering denudation determined the types of sediments in the basin formation. In addition, the later diagenesis and regional transformation should not be ignored. Therefore, it is believedthat the CIA value application must be combined closely with the traditional sediment facies and paleoclimate analysis, which can prevent any missing in the explanation and obtain the best results.