In this study, the effects of pH and temperature on adsorption and polymerization of glycine on anatase surface were investigated, respectively. The adsorption and polymerization capability of semiconductor minerals toward amino acid and the relevant mechanism were discussed. The results showed that the maximum adsorption capacity of glycine on anatase surface was obtained at pH=6.0. Under weak acid conditions, glycine was adsorbed by bonding the carboxyl group with functional groups or atoms on the anatase surface. Anatase catalyzed glycine polymerization in the range of 80~120℃ to form DKP, Gly₂, Gly₃ and other oligopeptides, suggesting that the catalytic polymerization products were controlled by temperature. The surface of anatase could provide active sites for the adsorption and condensation of glycine, and could further catalyze the polymerization of glycine when the enough energy (i.e., heating) was given.