The Shigente iron deposit is hosted in the volcano-sedimentary rocks of the Kangbutiebao Formation. The orebodies occur in bedding, lenticular, and vein forms, bounded by the strata. Skarnization and magnetite mineralization are both present in the ore district. The ore-forming process can be divided into volcanic sedimentary (the main mineralization period), magmatic hydrothermal (skarn-type mineralization period), and regional metamorphic periods. Magnetite in the volcanic sedimentary period and the retrograde alteration stage of the magmatic hydrothermal period is rich in Fe and depleted in Si, Ti, V, Mg, Mn. The chondrite-normalized REE patterns and primitive mantle-normalized trace element spider diagrams of magnetite show similar characteristics, which indicates that the iron mineralization in the volcanic sedimentary period and the retrograde alteration stage had the same metal source, namely the mafic volcanic rocks. Homogenization temperatures of fluid inclusions of garnets at the early skarn stage vary from 160 to 403℃, generally in the range of 180 to 260℃. Salinities range from 5% to 9% NaCleq; δD values range from -134‰ to -125‰, and δ¹⁸O_H2O values are between 4.7‰ and 8.6‰, implying that the fluids were derived from magmatic fluids. Homogenization temperatures of fluid inclusions in the quartz-carbonate stage vary from 140 to 536℃, mainly in the range of 160 to 340℃, and the salinities range from 6% to 16% NaCleq, which indicates that the fluids are characterized by the evolution from high to low temperatures, moderate-low salinities, and moderate-low densities. δD values of quartz range from -98‰ to -95‰, and δ¹⁸O_H2O values are between -0.6‰ and 2.0‰, showing that the fluids in this stage were derived from magmatic fluids, with some contributions from the meteoric water.