Cerebral artery calcification is closely associated with cerebrovascular diseases. In this study, mineralogical analytic techniques were applied to cerebral artery samples with atherosclerotic calcification, including scanning electron microscope(SEM), transmission electron microscope(TEM), micro-Fourier transform infrared spectroscopy(micro-FTIR), micro-area synchrotron radiation X-ray powder diffraction(μ_SRXRD) and micro-area synchrotron radiation X-ray fluorescence(μ_SRXRF). The results show that calcification mainly exists in two aggregated forms, i.e., spherical and massive. Spherical calcification has concentric layers or radiated-concentric structure, with a diameter of 0.3~5μm. Spherical calcification could be observed in the massive calcification, which is surrounded by randomly arranged prismatic crystals. The mineral phase of calcification is type-B carbonate hydroxyapatite(B-CHA), which contains Na, Mg, Zn, Fe and Sr. The mineral phase in calcification is similar to that of the minerals in cardiovascular artery calcification. Spherical calcification appears at the initial stage of calcification, which is eventually filled with CHA nanocrystals and developed into massive ca_lcification.