This paper reports some results of multi-purpose geochemical mapping in Qinghai Province. Soil heavy metal anomalies of such elements as Cd, Pb, Hg and Cr were detected in the narrow valley of Minhe and Haishiwan, along Road 109. The heavy metal anomalies exhibit features of relatively large anomalous area and high thresholds of anomalous elements. The results of correlation analysis show that Cr is significantly associated with soil constant components and negatively related to SiO₂. Cr is slightly concentrated in the top layer of soil in vertical section while urban areas have considerably higher level of Cr along the horizontal section. Cd is evidently associated with organic carbon, but there exists no such obvious correlation between Cd and TFe₂O₃. Beyond the soil depth of 80 cm, the content of Pb in the anomalous area is obviously higher than that in other areas. Pb anomaly basically exists at the surface of the soil. Hg is obviously concentrated at the surface of soil, while in the urban area it exists at the higher level. The results indicate that anthropogenic input is the main factor responsible for the formation of anomalies of Cd, Pb and Hg. The anthropogenic input increases the content of Cr in the high natural background. Therefore, we must control and manage the industrial "three wastes" in the anomalous area to prevent the expansion of the soil heavy metal anomaly.