On the basis of Fe isotope distribution in different reservoirs, the p resent situation of using Fe isotopes to trace mantle processes is reviewed in t his paper. Data obtained from mantle xenoliths hosted in Cenozoic basalts of North China confirm the existence of Fe isotope heterogeneity in the mantle. According to the previous and new data available, the mechanism for Fe isotope fractionation in mantle rocks is also discussed. It is pointed out that Fe isotopes have important potentials in tracing such mantle processes as mantle metasomatism, partial melting, and evolution of oxygen fugacity.