SR-XRF microprobe was used to measure elements in fluid inclusions hosted by quartz associated intimately with Cu mineralization of the Jiama and Nanmu deposits in the Gangdise copper-polymetallic metallogenic belt of Tibet. Analyses show that fluid inclusions from Jiama are rich in Cr and Pb but poor in Fe and Ni. In addition, fluid inclusions from Jiama show Pt and Ir anomalies, with the Pt and Ir concentrations higher than those of the continental crust. Fluid inclusions from Nanmu are rich in Cr, Cu and Pb but poor in Fe, Zn and Ni. In the Nanmu deposit, copper concentrations in highly saline fluid inclusions are by far higher than those in low salinity fluid inclusions and vapor inclusions, suggesting that copper selectively entered saline fluids. SR-XRF microanalysis also reveals that gold was concentrated in late-stage ore-forming fluids.Primitive mantle normalized patterns of the first transitional metal elements in fluid inclusions from Jiama and Nanmu are generally similar to those of mineralizing intrusives in the corresponding areas. These features imply that ore-forming fluids and ineralizing porphyries have similar material resources in Jiama and Nanmu districts. Both mantlederived and crust-derived materials contributed to mineralization. However, the ore-forming fluids did not originate from porphyries but evolved parallel to porphyries. SR-XRF microanalysis results of fluid inclusions fail to support submarine exhalation origin of the Jiama deposit.