Mineral-humus interactions are key interfacial processes for the environmental substances in soils, aquatic sediments and suspended particulates. The movement, transport and fate of either nutrient elements of nitrogen and phosphorus or heavy metals as well as toxic organic chemicals in the environment are regulated by the surface reactivity and movement of minerals, humic substances and their complexes. The research on the interface interactions of mineralhumus systems is a prospective field. The major objective in this study lies in describing such structural features of particulates as the layered structure and the micro-conformation and their relations with the reactivity of particulates and revealing the mechanism of mineral-humus interactions in soil and water environments. In this paper, the advances made in this field are reviewed and its future trend is predicted.