The interactions between minerals and microbes, which occur widely in nature and directly result in dissolution and formation of minerals, have profound impact on the environment. The interactions between minerals and microbes are helpful to remediation of the environment. The metal-reducing bacteria, for example, can degrade aromatic compounds like benzoate, benzene, toluene etc. through the oxidation process, or degrade (poly)nitroaromatic compounds and carbon tetrachloride through the reduction process by using Fe3 -oxide as the terminal electron acceptor. Microbes can cause some harmful elements such as U and Np to precipitate as insoluble mineral species through bacterial surface absorption or redox process. In addition, some microbes can actively oxidize sulphide minerals, resulting in the formation of acid mine drainage which is very hazardous to the environment.