The dissolubilities of fibrous clinoptilolite, sepiolite, palygorskite and chrysotile dusts in amino acid liquor at the simulated human body temperature (37℃) were investigated, and the changes of pH values and electric conductivity in the dissolving process in 72 hours were studied. The dissolution of fibrous minerals in amino acid is related to the acid types: the dissolution of fibrous minerals in acid amino acid (glutamic) is greater than that in neutral amino acid (valine), and the dissolution is weakest in alkaline amino acid (lysine). The dissolubility increased in the first 8 hours and then tended to be stable. The relative dissolution rates of fiber minerals in the same acid are: clinoptilolite < sepiolite and palygorskite < chrysotile, which shows that clinoptilolite has stronger corrosion_resisting ability and higher bio-resistibility, while chrysotile displays lower corrosion resistance.