The process of dissolution of fibrous wollastonite dust in amino acid aqueous solution at body's temperature 37℃was studied and the variations of pH and conductivity in 72 hours in the dissolution process were measured. Results suggest that the dissolution of wollastonite fibers in amino acids is related to the nature of acid: the capacity of mineral's dissolution is strongest in acid amino acids, less strong in neutral amino acids and weak in alkali amino acids. The sat- uration point appears in about 8 hours when the mineral is in acid and alkali amino acids, while in neutral amino acids no saturation point appears within 72 hours. The solubility has a trend of increasing linearly with time. The dissolution characters of wollastonite show that wollastonite's resistibility is not strong in nearly neutral body liquid. Metal ions can be remobilized by amino acids, and in the process of dissolution the organic reaction between metal ions and amino acids may damage the structure of amino acids to some extent, which may be one of the causes for the damage of normal protein.