The study of biological active and toxic effect of mineral particulates (dusts) and bacterial microorganisms is a new branch of environmental mineralogy just carried out both in China and abroad. Combined with the reserach situation of applied microorganisms such as microbiological and soil fertilizers, the extraction of microorganisms and elements, the removal of microbiological dirt and harmful elements, this paper deals emphatically with the action of microorganisms to mineral interfaces as well as their interdependent relationship, and points out the shortcomings in the study of the product and mechanism of bacteria/dust action under the condition of residential and atmospheric environment, ocean floor environment and polar environment as well as human body environment. It is held that emphasis should be placed on research work of mineral dusts/bacteria stem action and its environment_conditioning factors, the toxic effect of the process of dusts/bacteria action, the mutual selection between elements and bacteria in mixed dusts and the expression of the coordination body. It is probable that the major attention will be focused on such problems as the leading dynamic force of mineral/bacteria stem action and the action of auto_oxidized bacteria on dusts of silicate minerals. Importance will be attached to the mutual surface adsorption between mixed mineral dusts and microorganisms, the metabilites produced when mineral dusts enter microorganic system as well as the variation in the requirements for environmental vitamin and amino acid. The characteristics of crystal boundary and membrance boundary are emphasized.