Hydrogen and oxygen isotopic composition of altered rocks and ore-forming fluids proves to be one of the best indicators in the genetic study of hydrothermal deposits,and the determination of ini tial parameters of hydrogen and oxygen isotopes in the process of water_rock exchange seems to be of key importance. Based on an investigation into hydrogen and oxygen isotopic composition backgrounds of major geological bodies related to gold deposits in Jiaodong region, the present paper points out that the hydrogen and oxygen isotope background values are δ180=7.8% and δD=-110% for the Early Yanshanian "Linglong" medium-coarse grained adamellite (Luanjiahe type), δ180=10.0% and δD=-90% for the Late Yanshanian Guojialing type porphyritic granodiorite, δ180=8.5% and δD=-90% for the Kunyushan complex granitic batholith,and δ180=5.1-11.3%o and δD=-81--96%o for the metamorphic rocks of Jiaodong Group. These data show that the protoliths of the Jiaodong Group contained both mantlederived intermediate-basic components and crust-derived argillaceous-arenaceous materials,whereas the Guojialing type granite and regional intermediate-basic dikes are likely pro_ ducts of remelting and crystallization differentiation of other geological bodies in this region. Hydrogen and oxygen isotopic data of some subordinate rock bodies in this region are also given in this paper.