Muscovite is the important component of mineral aerosols in the atmosphere. The researches for heterogeneous reactions of common gases in the atmosphere on the surface of muscovite will reveal the chemical reaction process in the atmosphere to a certain extent. In this study, the heterogeneous reaction of SO₂ and NO₂ on the surface of muscovite particles was investigated by a self-made quartz glass microreactor, and the effects of relative humidity (RH) and light on the reaction were also discussed. The results showed that muscovite has certain adsorption activity for both SO₂ and NO₂. The products in SO₂ reaction with and without ultraviolet irradiation were mainly salt compounds containing SO^2-₄ and SO^2-₃, respectively, while the products in NO₂ reaction were always mainly salt compounds containing NO^-₃. The increase of RH or ultraviolet light had a promoting effect on the reaction, and they had a synergistic effect on the formation of sulfate and nitrate. When SO₂ and NO₂ coexist on the surface of muscovite, there were both synergistic effect and competitive effect, and the generation amount of SO^2-₄ and NO^-₃ was 2.09 times and 77% of that in the presence of a single gas, respectively. Therefore, NO₂ promoted the formation of sulfate, but SO₂ had a significant inhibitory effect on the formation of nitrate.