Located in the south margin of the Chinese Southwest Tianshan area, the Huoshibulake alkali feldspar granite pluton is composed mainly of alkali feldspar granite with a small amount of alkali feldspar granite porphyry. All samples from the pluton are characterized by high values of SiO2 and Al2O3 and low values of Fe2O3T, MgO, TiO2, P2O5. All samples are of alkaline affinities based on AR versus SiO2 diagram, and chiefly fall into the metaluminous area in the A/CNK versus A/NK diagram. The primitive mantle normalized trace element diagrams are characterized by the enrichment of the HFSE relative to the LILE, and negative anomalies of Sr, Ba, P, Ti. The samples exhibit a relative enrichment of LREE as well as strong negative anomalies of Eu, contain fluorite and have high ratios of FeOT/MgO and low values of CaO. The alkali feldspar granite pluton is also characterized by high 10000 Ga/Al ratios and Zr+Ni+Sr+Y values. Petrology and geochemistry of the pluton show that it belongs to typical A1-type granite, and is a product of the partial melting of the mafic lower crust in an intraplate environment. The low content of Ti results from a large quantity of residual magnetite minerals in the source area, and the high Nb-Ta value is caused by the enrichment of F in magmas. The tectonic setting is affected by the rift system within the Tarim Block. The pluton is rather insignificant in the study of the genesis of the Huoshibulake Pb-Zn deposit but displays Sn mineralization potential.