According to the observation of mineral compositions and assemblages of the amphibolites along the China-Pakistan highway profile in southern West Kunlun Mountains, it is held that the components of the volatiles directly affect the assemblages and compositions of amphibole, biotite, scapolite and titanite. Someone once believed that scapolite did not experience exolution, but this opinion seems not to stand. Pyrite rods are actually exsolved parallel to the {100} crystal faces, henceforth the state of sulfur in scapolite is most likely S2-, not SO4 2- . Scapolite is the reservoir of such volatiles as Cl, CO3 2- and S2- in the early metamorphic process. In the late shear deformation period, cooling and/or decompression result in the release of the volatiles, and the associated hydrothermal process might form metal sulfides and even lead to mineralization.